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This issue presents five articles addressing chemistry education and applied chemistry practices, ranging from analyses of chemistry content structure in the Merdeka Curriculum, the alignment of Thermochemistry materials with 21st-century skills and IUPAC standards, and teachers’ readiness in responding to limited instructional time, to a simple experimental study on compound distribution in green and black tea using RGB color analysis and a molecular docking study of galangal compounds against SARS-CoV-2 Mpro. Overall, this issue reflects an effort to promote more contextual, adaptive, and research-oriented chemistry learning through curriculum studies, classroom innovation, simple laboratory inquiry, and computational approaches.